Linzess may lead to several side effects, including the following:

• The most common side effect is diarrhea, which can occasionally become severe and usually starts within the first two weeks of treatment with Linzess. If you experience severe diarrhea while taking Linzess, discontinue the medication and contact your doctor immediately.
• Other common side effects of Linzess encompass gas, abdominal pain, and a sensation of fullness or pressure in the abdomen (distention).
• If you encounter unusual or severe abdominal pain, particularly if accompanied by bright red, bloody stools or black tar-like stools, seek immediate medical attention by contacting your doctor or visiting the nearest hospital emergency room.

It is important to note that these are not the only potential side effects of Linzess. For additional information regarding side effects, consult your doctor for medical advice.